How much time does it take to participate in the ADNI4 study?

ADNI is a 5-year study. We hope that our participants will stay involved in ADNI research activities for as long as possible. This will help us understand more about brain health and aging over time. If at any time you wish to stop participating in the study, you may do so.

If you join the ADNI Digital study, you will be asked to answer questions online about yourself and your health. You will also be asked to complete a memory test which will record your voice and responses. You will be asked to identify a “study partner” - a person who knows you well. They must be able to answer questions about your health and everyday functioning. A study partner is not needed for the study. The ADNI Digital study, including the online memory test, is expected to take about 15 to 20 minutes to complete.

 You do not have to do it all in one sitting. Your progress will be saved, so if you pause and log back in later, you will return to where you left off. You will have up to 30 days to complete your first visit to the ADNI online platform. We will invite you to return to the ADNI online platform every 6 months to repeat these tasks. Your participation over time allows us to better understand changes to brain health and memory. If you need assistance completing the online tests, please contact us at info@adni4.org or call our support team at 1-888-299-ADNI (2364). We’re here for you every step of the way.

If you join the second phase of the ADNI4 study, the Blood Biomarker portion, you will be asked to have a blood draw. This blood draw will be at a local Quest Diagnostics lab near you. We will provide you with instructions for how to make a blood draw appointment. Our study staff can help you book an appointment that is convenient for your schedule as well. Providing a blood sample should take less than thirty minutes. This does not include any travel to/from the Quest lab site. We may ask you to provide additional blood samples in the future and will reach out to you every 2 years to ask you to repeat the blood draw.

If you join the third phase of the ADNI4 study, the In-Clinic study, you will be asked to visit an ADNI4 clinical site located within 150 miles of where you live. At the clinic, healthcare professionals working with the ADNI study team will help you complete various tests. These tests will reveal information about your memory, thinking, and ability to carry out day-to-day activities. This will help us better understand brain health and Alzheimer’s disease. The study staff will also collect blood, urine, and other samples from you. Also, you will be asked to complete an MRI and/or PET scan which shows images of your brain. It allows us to study how the brain changes over time, especially with different health conditions including Alzheimer’s disease. Participants in the In-Clinic ADNI4 study will often complete these tasks over one to two days at the clinical site. Participants will be asked to return to the clinic every year over the five-year course of ADNI4.

If you have any questions about the ADNI4 study, we are here to help. Please contact us at info@adni4.org or call our support team at 1-888-299-ADNI (2364).